Osteochondrosis and Degenerative Changes of the Spine: Scientific Basis for the Use of the Natural Mineral Complex LUGELA

Intervertebral discs, endplates, neuromuscular regulation, and comprehensive spinal support
Author: Gelani Khalukhaev
Tbilisi, 2026
Main conclusion

Osteochondrosis represents a complex of degenerative changes in the intervertebral discs, vertebral bodies, endplates, joints, and ligamentous apparatus of the spine. Clinical manifestations are determined not only by the condition of the disc but also by muscle function, nerve structures, local blood supply, physical activity level, and the nature of the load.

The use of LUGELA in osteochondrosis has a documented medical basis: this nosology is included in the recommendations for internal and external use of therapeutic mineral water.

The basis of the course is oral intake, ensuring the supply of a natural complex of mineral ions. Local applications are used as an additional method of affecting the problem area.

LUGELA is included as part of a comprehensive approach alongside diagnostics, therapeutic exercise, load correction, and prescribed medical therapy.

What the term osteochondrosis means

In clinical practice, the term osteochondrosis of the spine denotes degenerative changes in the spinal motion segment. They affect the intervertebral disc, adjacent vertebral surfaces, facet joints, ligaments, and surrounding muscles.

In international medical literature, these conditions are described in more detail: intervertebral disc degeneration, spondylosis, facet arthrosis, radiculopathy, spinal canal stenosis, cervicalgia, and lumbalgia. Such differentiation helps to identify the source of pain and choose an appropriate treatment strategy.

Degenerative changes on X-ray or MRI are not equivalent to clinical disease. They are often found in people without pain or neurological disorders. Therefore, diagnosis is made based on the combination of complaints, neurological examination, and instrumental research results.

Intervertebral disc and its nutrition

The intervertebral disc consists of the nucleus pulposus, surrounding fibrous ring, and cartilaginous endplates. It distributes mechanical load, provides spinal mobility, and cushions pressure during walking, bending, and physical work.

The disc has almost no own blood supply. Oxygen, glucose, and other necessary substances reach its cells mainly by diffusion through the vertebral endplates. Metabolic waste products are removed through them as well. The condition of the endplates and the efficiency of substance transport are directly related to the preservation of the disc structure.

During degeneration, the content of proteoglycans and water in the nucleus pulposus decreases, disc elasticity reduces, and load distribution changes. Cracks form in the fibrous ring, intervertebral space height decreases, and the load on spinal joints and ligaments increases.

How pain syndrome develops

Pain in degenerative spinal diseases arises from several sources:

  • intervertebral discs and endplates;
  • facet joints;
  • ligaments and muscles;
  • inflammatory reaction in altered tissues;
  • irritation or compression of the nerve root;
  • disturbance of motor patterns and prolonged muscle spasm.

Irritation of the nerve root is accompanied by pain radiating to the arm or leg, numbness, tingling sensations, and muscle weakness. These signs require neurological evaluation, as radicular syndrome treatment differs from management of nonspecific back pain.

Pain restricts movement, and lack of movement reduces the strength of deep muscles stabilizing the spine. Load is distributed less efficiently, which maintains overload of certain segments. Therefore, restoration of motor activity and muscle function is a mandatory part of comprehensive treatment.

The importance of mineral exchange

The spinal motion segment includes not only the disc but also vertebral bone tissue, articular surfaces, muscles, ligaments, and nerve structures. Their normal function depends on full mineral metabolism.

Calcium performs several fundamental functions:

  • forms the mineral basis of bone tissue;
  • participates in muscle contraction;
  • ensures nerve impulse transmission;
  • regulates intracellular signaling processes;
  • supports cardiovascular and endocrine system functions.
Scientific accuracy requires distinguishing the condition of the intervertebral disc from bone mineralization. Calcium intake does not mean direct restoration of the damaged disc. Its physiological role lies in maintaining the vertebrae's bone structure, neuromuscular transmission, and general regulatory processes upon which spinal function depends.

The natural ionic matrix of LUGELA

LUGELA belongs to highly mineralized natural chloride-calcium therapeutic waters. Its properties are determined not by a single isolated substance but by an integral natural ionic system.

High calcium content combines with chlorides and other components of the natural mineral complex. That is why LUGELA should not be equated with pharmaceutical calcium chloride solution. Historical experimental and clinical studies have considered it as a standalone natural therapeutic factor.

The natural mineral composition of LUGELA provides ions involved in the functioning of bone, nervous, muscular, and vascular systems. This creates a physiological basis for its use in musculoskeletal support programs.

Documented basis for use

In the balneological and medical conclusion of 2023, osteochondrosis is included in the list of musculoskeletal diseases for which the use of therapeutic mineral water LUGELA is recommended.

Documents provide two complementary directions:

  1. Oral intake: the basic method of systemic use of the natural mineral complex.
  2. External application: additional local effect on the problem area.

This approach corresponds to the nature of the disease: degenerative changes in the spine are associated simultaneously with local tissue processes and the general state of musculoskeletal, nervous, and vascular systems.

Oral course as the basis of use

The standard monthly course of LUGELA consists of four bottles of 235 ml each, totaling 940 ml.

According to the adult instructions, LUGELA is taken 10 ml three times a day after meals, rinsed down with 40–50 ml of warm water. The specific regimen is determined by official instructions and individual medical recommendations.

The course intake ensures regular supply of the natural mineral complex. Single or irregular intakes do not correspond to the principle of systemic use of therapeutic mineral water.

In cases of kidney disease, calcium metabolism disorders, and simultaneous drug intake, the course should be agreed with a specialist.

Contraindications include hypercalcemia and individual intolerance to components.

Local application

For pain and functional tension in the neck, thoracic, or lumbar region, external use of LUGELA complements the oral course.

Local application is directed specifically to the problem area and is used as part of a comprehensive program. It does not replace systemic intake, diagnostics, therapeutic exercises, and prescribed medical treatment.

The method, duration, and frequency of applications are determined by the recommendations for external use of LUGELA and the nature of clinical manifestations.

The place of LUGELA in the comprehensive approach

Modern management of degenerative spinal diseases is based on combining several directions:

  • maintaining allowable daily activity;
  • therapeutic exercises and muscle strengthening;
  • correcting prolonged static load;
  • body weight control;
  • restoration of proper motor patterns;
  • medication therapy as indicated;
  • rehabilitation methods;
  • course use of LUGELA according to recommendations.

The World Health Organization characterizes low back pain as the leading cause of disability worldwide and emphasizes the importance of rehabilitation to restore activity and function.

Clinical guidelines prescribe maintaining activity and using exercise programs based on patient condition.

Instrumental diagnostics are performed when the result may influence treatment tactics.

When urgent diagnostics are required

Back pain requires urgent medical evaluation if the following signs appear:

  • increasing weakness in arm or leg;
  • urination or bowel control disturbances;
  • perineal numbness;
  • severe pain after injury;
  • fever or signs of systemic infection;
  • unexplained weight loss;
  • history of cancer;
  • rapid progression of neurological deficits.

In these situations, use of the natural therapeutic agent should not delay medical examination.

Scientific significance of LUGELA use

The scientific value of the approach lies in the combination of three levels:

  • physiology of mineral metabolism;
  • systemic support of bone and neuromuscular functions;
  • documented recommendation of LUGELA in osteochondrosis.

LUGELA is not considered a means of mechanical restoration of a destroyed intervertebral disc. Its role is defined more precisely: the natural therapeutic mineral complex is used to support physiological processes related to the musculoskeletal system's state and is included in a comprehensive program for degenerative spinal diseases.

This formulation maintains scientific accuracy and simultaneously reflects the area of product use established by medical documents.

Academic conclusion

Osteochondrosis is a multifactorial degenerative process affecting intervertebral discs, endplates, joints, ligaments, muscles, and nerve structures. Its clinical course is determined not only by anatomical changes but also by load characteristics, muscle stabilization condition, neural regulation, and overall musculoskeletal function.

The natural mineral complex LUGELA holds a justified place in the comprehensive approach to osteochondrosis. The oral course is the basis for systemic use, and local applications complement it by affecting the problem area. Medical and balneological conclusions of 2023 document osteochondrosis among the indications for LUGELA use.

A rational program combines course intake of LUGELA, motor rehabilitation, load correction, medical diagnostics, and prescribed therapy. It is the comprehensive approach that creates conditions for pain reduction, mobility restoration, and spinal function maintenance.

Main sources

  1. World Health Organization. Low back pain. 2023.
  2. World Health Organization. WHO guideline for non-surgical management of chronic primary low back pain in adults. Geneva, 2023.
  3. National Institute for Health and Care Excellence. Low back pain and sciatica in over 16s: assessment and management. NG59.
  4. Urban J. P. G., Roberts S. Degeneration of the intervertebral disc. Arthritis Research & Therapy. 2003.
  5. Urban J. P. G., Smith S., Fairbank J. C. T. Nutrition of the intervertebral disc. Spine. 2004.
  6. Brinjikji W. et al. Systematic literature review of imaging features of spinal degeneration in asymptomatic populations. AJNR. 2015;36(4):811–816.
  7. Balneological conclusion on therapeutic mineral water LUGELA. 2023.
  8. Medical conclusion on internal and external use of therapeutic mineral water LUGELA. 2023.
  9. Instructions for the course use of therapeutic mineral water LUGELA.