BIBLIOGRAPHY

Scientific works, publications and documentary sources

The scientific bibliography of LUGELA combines monographs, dissertation research, experimental and clinical works, articles, collected works and other materials in which the composition, physiological properties, and medical use of the therapeutic mineral water Lugela were studied.

Its purpose is not to duplicate the content of the Scientific Library, but to provide doctors and researchers with a unified systematic index of scientific sources with the ability to access the original document.

The scientific study of Lugela developed sequentially: from chemical analysis of the source and general characteristics of the water to experimental pharmacology, investigation of individual physiological mechanisms, and clinical application. This continuity is well traced in the bibliographic materials of later scientific works. For instance, the dissertation of N. V. Glonti contains a separate literature index and refers to fundamental works on Lugela from the mid-20th century.

Key scientific sources of LUGELA

"On the mineral water of Mukhuri"

Javakhishvili D. V. In the collection: Chloride-calcium mineral water of Mukhuri. 1945. Pp. 3–8.

This work is among the fundamental sources from the early period of scientific study of the water and the formation of the idea of Lugela as a special natural therapeutic factor.

"Mineral water Lugela"

Javakhishvili D. V. Soviet Medicine. 1949. No. 5. Pp. 33–34.

"Mineral water Lugela: characteristics and therapeutic properties"

Javakhishvili D. V. Research Institute of Balneology and Physical Therapy of the Ministry of Health of the Georgian SSR. Tbilisi, 1953.

These three works by D. V. Javakhishvili form one of the central lines of Lugela's scientific heritage. Later research repeatedly referred to them when describing the chemical composition, therapeutic properties, and features of the natural water complex.

Experimental pharmacology

"Experimental pharmacological study of the mineral water Lugela"

Gvishiani G. S., Khukhia V. P. Bulletin of Experimental Biology and Medicine. 1951. Pp. 221–224.

This work marks a crucial stage in transitioning from describing the water's composition to experimental evaluation of its physiological and pharmacological effects.

"Pharmacodynamic significance of certain ingredients in the mineral water Lugela"

Gvishiani G. S., Gvitsaridze V. L. Abstract collection of works of the State Scientific Research Institute of Balneology and Physiotherapy. Vol. 21. Tbilisi, 1954. Pp. 122–124.

These studies are especially important for understanding why the effect of natural Lugela cannot be considered as the action of one isolated mineral component alone.

Clinical dermatology

"Therapy of eczema with natural therapeutic Lugela water"

Glonti N. V. Dissertation for the degree of Candidate of Medical Sciences. Tbilisi State Medical Institute; Scientific Research Dermatovenerology Institute of the Ministry of Health of the Georgian SSR. Tbilisi, 1970.

The work includes a literature review, characteristics of Lugela, comparative study with artificial calcium chloride solution, original clinical and laboratory observations, conclusions, and practical recommendations.

The dissertation is particularly significant for dermatology as it directly investigates oral and topical use of Lugela in eczema and presents the author's practical conclusions.

Research on the body's protective mechanisms

Andguladze I. G.

"Dissertation study on the influence of mineral water Lugela on the functional state of active mesenchyme in tuberculosis"

The work covers the history of Lugela research, source geography, chemical composition, experimental studies, and the water's effect on the body's protective mechanisms. Special attention is given to the functional state of the active mesenchyme and physiological responses of the organism.

The dissertation characterizes Lugela as a mineral water with an exceptionally rare chemical composition; the author also provides information about its recognition as therapeutic water by the Scientific Council of the Ministry of Health of the USSR in 1945.

Bibliography as a developing scientific index

The scientific heritage of LUGELA is much broader than a few fundamental works.

Bibliographic indexes of dissertations and monographs present works on:

• chemical composition of the water;

• experimental pharmacology;

• calcium and mineral metabolism;

• gastric secretion;

• inflammatory processes;

• vascular permeability;

• hemostasis;

• dermatology;

• allergic reactivity;

• body protective mechanisms;

• various clinical applications.

Importance of the bibliography

The LUGELA bibliography fulfills several functions at once.

It shows the sequence of scientific study of the water, enables tracing the origin of specific conclusions, and creates a direct link between Encyclopedia articles and original scientific works.

For physicians, it serves as a pointer to the evidence base.

For researchers, it allows following the development of the Lugela scientific concept.

For medical historians, it preserves the documentary continuity of scientific research.

Conclusion

The LUGELA bibliography systematizes the main scientific sources dedicated to studying the composition, properties, and medical use of Lugela.

It unites bibliographic information on scientific works and documents and provides connections between the materials of the LUGELA Encyclopedia, Scientific Library, and original sources.

As new documents are digitized and prepared, the bibliography may be supplemented and expanded.

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